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Cirrhosis represents a late stage of progressive hepatic fibrosis characterized by distortion of the hepatic architecture and the formation of regenerative nodules. It is generally considered to be irreversible in its advanced stages, at which point the only option may be liver transplantation. In earlier stages, specific treatments aimed …

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The prevention and treatment of iron deficiency is a major public health goal, especially in females, children, and individuals in low-income countries. Challenges in the treatment of iron deficiency include finding and addressing the underlying cause and the selection of an iron replacement product that meets the needs of the patient. This ...In February 2020, the World Health Organization (WHO) designated the disease COVID-19, which stands for coronavirus disease 2019 [ 1 ]. The WHO declared an end to the COVID-19 global health emergency in May 2023, more than three years after its emergence. This topic will discuss the virology, epidemiology, and prevention of COVID-19.Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or …Spontaneous bacterial peritonitis (SBP) is defined as an ascitic fluid infection without an evident intra-abdominal surgically treatable source [ 1 ]. The presence of SBP, which almost always occurs in patients with cirrhosis and ascites, is suspected because of suggestive signs and symptoms, such as fever, abdominal pain, or altered mental ...

UpToDate: Industry-leading clinical decision support for enterprises. Medical information updates daily. Your care teams and leadership need the best evidence and clinical …Immune thrombocytopenia (ITP) is an acquired thrombocytopenia characterized by immune-mediated destruction of platelets and/or impairment of platelet production; terminology is summarized in the table ( table 1 ). ITP is a diagnosis of exclusion; there are no reliable laboratory tests to confirm the diagnosis.

May 3, 2024 ... Outline · Zanubrutinib plus obinutuzumab in multiply relapsed follicular lymphoma (April 2024) · Three-year follow-up of CAR-T cell therapy in .....

Apr 1, 2024 · For over a century, open appendectomy was the only standard treatment for appendicitis. Contemporary management of appendicitis is more sophisticated and nuanced: laparoscopic appendectomy has surpassed open appendectomy in usage, some patients with perforated appendicitis may benefit from initial antibiotic therapy followed by interval ... Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options.Multiple antibiotic regimens have been evaluated for Helicobacter pylori ( H. pylori) therapy [ 1-6 ]. However, few regimens have consistently achieved high eradication rates. There are also limited data on H. pylori antibiotic resistance rates to guide therapy. The treatment regimen that is selected must consider local antibiotic resistance ...As the condition progresses, most people eventually have inflammation of the joints in the arms or legs. Less commonly, some people have inflammation of the hips and in the upper part of the spine. Joint symptoms — Joint-related symptoms typically include stiffness, pain, redness, warmth to the touch, and swelling.Get the clinical information you need with a personal subscription to UpToDate. Trusted for more than 30 years, UpToDate® is the clinical decision support resource that provides …

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Feb 12, 2024 · Although hypokalemia can be transiently induced by the entry of potassium into the cells, most cases result from unreplenished gastrointestinal or urinary losses due, for example, to vomiting, diarrhea, or diuretic therapy [ 1-3 ]. (See "Causes of hypokalemia in adults" .) Potassium replacement is primarily indicated when hypokalemia is due to ...

UpToDate: Industry-leading clinical decision support for enterprises. Medical information updates daily. Your care teams and leadership need the best evidence and clinical …Oct 31, 2023 · Atrial fibrillation (AF) is the most commonly treated cardiac arrhythmia. AF is generally associated with an irregularly irregular ventricular rhythm and absence of distinct P waves. This topic will provide a broad overview of the classification, clinical presentation, diagnosis, management, and sequelae of AF, including new-onset AF. Oct 25, 2023 ... Outline · - Discontinuing hypertonic saline used as initial therapy · - Fluid restriction · - Other therapies for chronic hyponatremia ·...Once the diagnosis of either UA or an acute NSTEMI is made, the acute management of the patient involves the simultaneous achievement of several goals: Relief of ischemic pain. (See 'Initial medical therapy' below.) Assessment of the patient's hemodynamic status and correction of abnormalities. Hypertension and tachycardia, both …Janie asks, “Can hollow core doors be shaved off at the top like solid wood doors?”Hollow core doors typically have about one inch of solid wood at the top and bottom, so you shoul...

For over 30 years, clinicians around the world have trusted the evidence-based content in the UpToDate® clinical decision support (CDS) system to help make crucial care decisions when it matters most. Founded by clinicians for clinicians, and backed by an expert editorial team in over 25 specialties, UpToDate provides the latest medical ...From the laboratory to your medicine cabinet, the process of researching and developing a drug is long, complicated and costly. From the laboratory to your medicine cabinet, the pr...The four essential components of asthma management are patient education, minimizing exposure to asthma triggers, monitoring for changes in symptoms or lung function, and pharmacologic therapy. This overview topic presents the goals and components of asthma management. It is applicable to both children and adults.Powerful and practical clinical knowledge at your fingertips, a personal subscription to UpToDate provides consistent, convenient access to enhance your daily medical practice. UpToDate helps you stay current on the latest evidence-based recommendations across 25 specialties to find answers to your clinical questions. Subscribe.The prevention and treatment of iron deficiency is a major public health goal, especially in females, children, and individuals in low-income countries. Challenges in the treatment of iron deficiency include finding and addressing the underlying cause and the selection of an iron replacement product that meets the needs of the patient. This ...Acute pancreatitis should be suspected in patients with severe acute upper abdominal pain but requires biochemical or radiologic evidence to establish the diagnosis. This topic will review the clinical manifestations and diagnosis of acute pancreatitis. The etiology, pathogenesis, assessment of severity, and management of acute pancreatitis are ...

Justin Bufkin of One Smile Closer shares how he started a photography business on the side. He shares tips on anyone can make money with photography. Part-Time Money® Make extra mo...This topic will review the clinical presentation, diagnosis, and initial evaluation of diabetes in nonpregnant adults. Screening for and prevention of diabetes, the etiologic classification of diabetes mellitus, the treatment of diabetes, as well as diabetes during pregnancy are discussed separately. (See "Screening for type 2 diabetes mellitus" .)

If your organization permits Single Sign-On (SSO) for UpToDate, you may use your email address here. If not, please enter your Username. Close Subscribe. Subscribe. UpToDate offers a number of subscriptions and add-on products, allowing you to have the most up-to-date information and improve patient care. About Us ...However, daytime use of CR tablets may exacerbate motor fluctuations and can lead to delayed-onset dyskinesia. Carbidopa-levodopa extended-release (ER) capsules show promise in reducing motor complications, but more widespread use is limited by cost and difficulties of converting from levodopa tablets to ER capsules.Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options.Cellulitis is an infection of the skin and underlying soft tissue. The infection is usually caused by bacteria, such as staphylococci ("Staph") or streptococci ("Strep"); these commonly live on the skin or inner surface of the nose or mouth among healthy people. For many people, these skin bacteria never cause infection.For over 30 years, clinicians around the world have trusted the evidence-based content in the UpToDate® clinical decision support (CDS) system to help make crucial care decisions when it matters most. Founded by clinicians for clinicians, and backed by an expert editorial team in over 25 specialties, UpToDate provides the latest medical ...Sign in with Microsoft. Sign in with Open Athens. Sign in Another Way. If your organization permits Single Sign-On (SSO) for UpToDate, you may use your email address here.Allergic conjunctivitis is caused by airborne allergens contacting the eye, which leads to immunoglobulin E (IgE) mediated local mast cell degranulation and allergic inflammation. It typically presents as bilateral ocular itching, redness, and watery discharge. This topic discusses the management of allergic conjunctivitis.Display complete list of interactions for an individual item by clicking item name. Add another item to analyze for potential interactions. NOTE: This tool does not address chemical compatibility related to I.V. drug preparation or administration. View interaction detail by clicking on link (s) below.The four essential components of asthma management are patient education, minimizing exposure to asthma triggers, monitoring for changes in symptoms or lung function, and pharmacologic therapy. This overview topic presents the goals and components of asthma management. It is applicable to both children and adults.

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Oct 31, 2023 · Atrial fibrillation (AF) is the most commonly treated cardiac arrhythmia. AF is generally associated with an irregularly irregular ventricular rhythm and absence of distinct P waves. This topic will provide a broad overview of the classification, clinical presentation, diagnosis, management, and sequelae of AF, including new-onset AF.

Vaginitis is the general term for disorders of the vagina caused by infection, inflammation, or changes in the normal vaginal flora. Symptoms include abnormal vaginal discharge, odor, pruritus, and/or discomfort. The initial evaluation typically consists of a history, physical examination, and tests for specific infections, including sexually ...Acute pancreatitis is an acute inflammatory process of the pancreas. Overall mortality rates in acute pancreatitis are approximately 2 percent, but can be as high as 30 percent in patients with persistent organ failure (severe acute pancreatitis) [ 1 ]. This topic reviews the management of acute pancreatitis.The pharmacology, efficacy, contraindications, and side effects of metformin for the treatment of diabetes will be reviewed here. A general discussion of initial treatment of type 2 diabetes and the role of metformin in the prevention of diabetes, in the treatment of polycystic ovary syndrome, and in gestational diabetes are reviewed separately.Our approach to pharmacologic therapy in patients whose systolic blood pressure falls by more than 10 to 20 mmHg after changing from a seated to upright posture is as follows: Choice of pharmacologic therapy – The choice of therapy is generally the same as in patients without orthostatic blood pressure changes.Mar 28, 2024 · Choice of initial therapy in most patients — The three primary options for antihypertensive drug therapy in most patients include an ACE inhibitor (or ARB), a calcium channel blocker, or a thiazide diuretic (preferably a thiazide-like diuretic) [ 3 ]. UpToDate is an online platform that offers evidence-based clinical information and decision support for health care professionals and patients. To use UpToDate, you need to create an account or log in with your credentials.Vaginitis is the general term for disorders of the vagina caused by infection, inflammation, or changes in the normal vaginal flora. Symptoms include abnormal vaginal discharge, odor, pruritus, and/or discomfort. The initial evaluation typically consists of a history, physical examination, and tests for specific infections, including sexually ...Clostridioides difficile infection (CDI) is one of the most common hospital-acquired (nosocomial) infections and is an increasingly frequent cause of morbidity and mortality among older adult hospitalized patients [ 1-3 ]. CDI is also increasingly diagnosed in younger patients and in the community.INTRODUCTION. —. Acute rhinosinusitis (ARS) is defined as symptomatic inflammation of the nasal cavity and paranasal sinuses ( figure 1) lasting less than four weeks. The term "rhinosinusitis" is preferred to "sinusitis" since inflammation of the sinuses rarely occurs without concurrent inflammation of the nasal mucosa [ 1 ].

Intravenous thrombolysis can be administered up to 4.5 hours after symptom onset, and mechanical thrombectomy can be administered up to 24 hours after symptom onset. (See "Approach to reperfusion therapy for acute ischemic stroke" and "Intravenous thrombolytic therapy for acute ischemic stroke: Therapeutic use" and "Mechanical …Feb 27, 2024 ... GRAPHICS · - Microbiologic diagnosis necrotizing infection · - Necrotizing fasciitis versus pyoderma gangrenosum · - MRSA parenteral antibioti...Dec 11, 2023 · Patient level information — UpToDate offers two types of patient education materials. The Basics — The Basics patient education pieces answer the four or five key questions a patient might have about a given condition. These articles are best for patients who want a general overview and who prefer short, easy-to-read materials. Management of patients with nausea and vomiting of pregnancy (NVP) depends upon symptom severity, the impact of symptoms on health and quality of life, and the safety of treatment for both mother and fetus. NVP is typically a self-limited condition and not associated with adverse pregnancy outcomes. Treatment approaches …Instagram:https://instagram. santander banks Cellulitis — The most common symptom of cellulitis is dull pain or tenderness in the area of skin involvement. Other cellulitis symptoms can include swelling, warmth, and redness in a distinct area of skin. These symptoms commonly worsen, and the redness may expand over the course of hours to days. The onset of cellulitis may be … chicago o'hare to boston Epilepsy is the syndrome of two or more unprovoked seizures that occur more than 24 hours apart [ 1 ]. Seizures affect people in many different ways. Seizures are disruptive in the lives of patients and can cause injury. People with epilepsy have higher rates of psychiatric comorbidity and may experience adverse psychosocial outcomes. video for childrens Apr 5, 2024 ... Outline · - Respiratory/airborne transmission as primary route · - Minimal role of other person-to-person routes · - Viral shedding and period&... photo clearer Sign in with Microsoft. Sign in with Open Athens. Sign in Another Way. If your organization permits Single Sign-On (SSO) for UpToDate, you may use your email address here. If …Cellulitis — The most common symptom of cellulitis is dull pain or tenderness in the area of skin involvement. Other cellulitis symptoms can include swelling, warmth, and redness in a distinct area of skin. These symptoms commonly worsen, and the redness may expand over the course of hours to days. The onset of cellulitis may be … airports in vietnam The clinical features of KD reflect widespread inflammation of primarily medium-sized muscular arteries. Diagnosis is based upon evidence of systemic inflammation (eg, fever) in association with signs of mucocutaneous inflammation. The characteristic bilateral nonexudative conjunctivitis, erythema of the lips and oral mucosa, …Oct 31, 2023 · Atrial fibrillation (AF) is the most commonly treated cardiac arrhythmia. AF is generally associated with an irregularly irregular ventricular rhythm and absence of distinct P waves. This topic will provide a broad overview of the classification, clinical presentation, diagnosis, management, and sequelae of AF, including new-onset AF. facebook web login mobile INTRODUCTION. The management of infective endocarditis (IE) includes prompt diagnosis, treatment with antimicrobial therapy, and in some cases of complicated IE, surgical management. Preventive measures including antimicrobial prophylaxis may reduce the risk of initial and recurrent IE for patients with relevant risk factors. dominoes game online free Gastroesophageal reflux disease (GERD) is notable for its high prevalence, variety of clinical presentations, under-recognized morbidity, and substantial economic consequences. This topic will review the clinical manifestations and diagnosis of GERD. The pathophysiology and management of GERD are discussed in detail separately.CAUSES OF VITAMIN D DEFICIENCY. The main reasons for low levels of vitamin D are: Lack of vitamin D in the diet, often in conjunction with inadequate sun exposure. Reduced absorption of vitamin D from the intestines. Reduced processing of vitamin D due to kidney or liver disease. proxy website browser UpToDate offers clinical, drug, and patient content to support health professionals wherever care takes place. Learn about subscription options, expert editorial content, access at the point of care, and improved health outcomes with UpToDate.Janie asks, “Can hollow core doors be shaved off at the top like solid wood doors?”Hollow core doors typically have about one inch of solid wood at the top and bottom, so you shoul... gujarati calendar 2024 Severe sepsis in adults: Rapid overview of emergency management during first hour. Table 1. Securing the airway (if indicated), correcting hypoxemia, and establishing venous access for the early administration of fluids and antibiotics are priorities in the management of patients with sepsis and septic shock [ 3,4 ]. best day travel Vitamin D decreases bone loss and lowers the risk of fracture, especially in older adults. Along with calcium, vitamin D also helps to prevent and treat osteoporosis. Adequate vitamin D is needed for efficient calcium absorption. Vitamin D is normally made in the skin after exposure to sunlight. (See "Patient education: Vitamin D deficiency ... six abc news This topic will focus on the treatment of hypernatremia induced by water loss, which is the most common cause. The treatment of hypernatremia in patients with impaired thirst, with or without arginine vasopressin disorders, and with primary sodium overload will also be reviewed. The causes and evaluation of patients with hypernatremia and the ...Generalized anxiety disorder (GAD) is characterized by excessive worry and anxiety that are difficult to control, cause significant distress and impairment, and occur on more days than not for at least six months [ 1 ]. GAD is a relatively common disorder, most often with an adult onset and chronic course [ 2-6 ].OS X Mountain Lion brought with it a world of new keyboard shortcuts and trackpad gestures that make working with your Mac faster and easier. We're still getting used to many of th...